This Week's Fixtures
New York City FC
v
Nashville SC
USA · Major League Soccer
Fri 4 Sep, 23:30 UTC
Both teams to score
· 58% model probability
· odds 1.62
Model
Goals 2.8
Corners 9.2 (4.6H · 4.7A)
Cards 4.2
BTTS 58%
O2.5 53%
Odds
Home 2.90
Draw 3.50
Away 2.30
BTTS 1.62
O2.5 1.80
Inter Miami
v
Atlanta United FC
USA · Major League Soccer
Sat 5 Sep, 23:30 UTC
Inter Miami to win
· 72% model probability
· odds 1.33
Model
BTTS 66%
O2.5 78%
Odds
Home 1.33
Draw 5.50
Away 8.00
BTTS 1.44
O2.5 1.25
Philadelphia Union
v
CF Montreal
USA · Major League Soccer
Sat 5 Sep, 23:30 UTC
Philadelphia Union to win
· 66% model probability
· odds 1.44
Model
BTTS 58%
O2.5 66%
Odds
Home 1.44
Draw 5.00
Away 6.50
BTTS 1.62
O2.5 1.44
FC Cincinnati
v
DC United
USA · Major League Soccer
Sat 5 Sep, 23:30 UTC
FC Cincinnati to win
· 60% model probability
· odds 1.57
Model
BTTS 64%
O2.5 68%
Odds
Home 1.57
Draw 4.33
Away 5.50
BTTS 1.50
O2.5 1.40
Orlando City SC
v
San Diego
USA · Major League Soccer
Sat 5 Sep, 23:30 UTC
Both teams to score
· 71% model probability
· odds 1.36
Model
BTTS 71%
O2.5 71%
Odds
Home 2.15
Draw 3.90
Away 3.10
BTTS 1.36
O2.5 1.36
Columbus Crew
v
Colorado Rapids
USA · Major League Soccer
Sat 5 Sep, 23:30 UTC
Columbus Crew to win
· 49% model probability
· odds 1.95
Model
BTTS 55%
O2.5 52%
Odds
Home 1.95
Draw 3.75
Away 3.60
BTTS 1.67
O2.5 1.80
Toronto FC
v
Chicago Fire
USA · Major League Soccer
Sat 5 Sep, 23:30 UTC
Both teams to score
· 63% model probability
· odds 1.50
Model
BTTS 63%
O2.5 60%
Odds
Home 2.88
Draw 3.70
Away 2.30
BTTS 1.50
O2.5 1.57
Charlotte
v
Houston Dynamo
USA · Major League Soccer
Sat 5 Sep, 23:30 UTC
Both teams to score
· 59% model probability
· odds 1.57
Model
BTTS 59%
O2.5 55%
Odds
Home 2.20
Draw 3.50
Away 3.20
BTTS 1.57
O2.5 1.70
Seattle Sounders
v
New York Red Bulls
USA · Major League Soccer
Sun 6 Sep, 00:30 UTC
Seattle Sounders to win
· 52% model probability
· odds 1.83
Model
BTTS 68%
O2.5 69%
Odds
Home 1.83
Draw 4.00
Away 3.90
BTTS 1.40
O2.5 1.40
FC Dallas
v
Sporting Kansas City
USA · Major League Soccer
Sun 6 Sep, 00:30 UTC
FC Dallas to win
· 66% model probability
· odds 1.45
Model
BTTS 58%
O2.5 65%
Odds
Home 1.45
Draw 5.00
Away 6.50
BTTS 1.62
O2.5 1.44
Austin
v
San Jose Earthquakes
USA · Major League Soccer
Sun 6 Sep, 00:30 UTC
Both teams to score
· 64% model probability
· odds 1.50
Model
BTTS 64%
O2.5 61%
Odds
Home 2.20
Draw 3.75
Away 3.00
BTTS 1.50
O2.5 1.53
Real Salt Lake
v
Los Angeles FC
USA · Major League Soccer
Sun 6 Sep, 01:30 UTC
Both teams to score
· 61% model probability
· odds 1.57
Model
BTTS 61%
O2.5 57%
Odds
Home 2.60
Draw 3.70
Away 2.50
BTTS 1.57
O2.5 1.67
Los Angeles Galaxy
v
New England Revolution
USA · Major League Soccer
Sun 6 Sep, 01:30 UTC
Both teams to score
· 65% model probability
· odds 1.44
Model
BTTS 65%
O2.5 63%
Odds
Home 2.40
Draw 3.75
Away 2.70
BTTS 1.44
O2.5 1.53
Vancouver Whitecaps
v
St. Louis City
USA · Major League Soccer
Sun 6 Sep, 02:30 UTC
Vancouver Whitecaps to win
· 67% model probability
· odds 1.45
Model
BTTS 59%
O2.5 66%
Odds
Home 1.45
Draw 5.00
Away 6.50
BTTS 1.62
O2.5 1.44
Portland Timbers
v
Minnesota United FC
USA · Major League Soccer
Sun 6 Sep, 02:30 UTC
Both teams to score
· 64% model probability
· odds 1.50
Model
BTTS 64%
O2.5 62%
Odds
Home 2.10
Draw 3.70
Away 3.30
BTTS 1.50
O2.5 1.53
Philadelphia Union
v
FC Cincinnati
USA · Major League Soccer
Wed 9 Sep, 23:30 UTC
Philadelphia Union to win
· 56% model probability
· odds 1.73
Model
BTTS 66%
O2.5 68%
Odds
Home 1.73
Draw 4.20
Away 4.00
BTTS 1.40
O2.5 1.40
Atlanta United FC
v
Orlando City SC
USA · Major League Soccer
Wed 9 Sep, 23:30 UTC
Both teams to score
· 65% model probability
· odds 1.44
Model
BTTS 65%
O2.5 64%
Odds
Home 2.05
Draw 3.80
Away 3.10
BTTS 1.44
O2.5 1.50
Toronto FC
v
Nashville SC
USA · Major League Soccer
Wed 9 Sep, 23:30 UTC
Both teams to score
· 62% model probability
· odds 1.50
Model
BTTS 62%
O2.5 59%
Odds
Home 2.90
Draw 3.60
Away 2.20
BTTS 1.50
O2.5 1.57
DC United
v
Columbus Crew
USA · Major League Soccer
Wed 9 Sep, 23:30 UTC
Both teams to score
· 61% model probability
· odds 1.53
Model
BTTS 61%
O2.5 57%
Odds
Home 2.35
Draw 3.50
Away 2.70
BTTS 1.53
O2.5 1.65
CF Montreal
v
Charlotte
USA · Major League Soccer
Wed 9 Sep, 23:30 UTC
Both teams to score
· 64% model probability
· odds 1.50
Model
BTTS 64%
O2.5 61%
Odds
Home 2.30
Draw 3.70
Away 2.75
BTTS 1.50
O2.5 1.53
New York City FC
v
New England Revolution
USA · Major League Soccer
Thu 10 Sep, 00:00 UTC
Both teams to score
· 61% model probability
· odds 1.57
Model
BTTS 61%
O2.5 58%
Odds
Home 2.05
Draw 3.60
Away 3.25
BTTS 1.57
O2.5 1.67
Chicago Fire
v
Inter Miami
USA · Major League Soccer
Thu 10 Sep, 00:30 UTC
Both teams to score
· 74% model probability
· odds 1.28
Model
BTTS 74%
O2.5 75%
Odds
Home 2.15
Draw 4.00
Away 2.80
BTTS 1.28
O2.5 1.28
Minnesota United FC
v
FC Dallas
USA · Major League Soccer
Thu 10 Sep, 00:30 UTC
Both teams to score
· 59% model probability
· odds 1.62
Model
BTTS 59%
O2.5 56%
Odds
Home 1.95
Draw 3.70
Away 3.50
BTTS 1.62
O2.5 1.67
Austin
v
Colorado Rapids
USA · Major League Soccer
Thu 10 Sep, 00:30 UTC
Both teams to score
· 58% model probability
· odds 1.62
Model
BTTS 58%
O2.5 53%
Odds
Home 2.40
Draw 3.50
Away 2.70
BTTS 1.62
O2.5 1.75
Houston Dynamo
v
Real Salt Lake
USA · Major League Soccer
Thu 10 Sep, 00:30 UTC
Houston Dynamo to win
· 56% model probability
· odds 1.67
Model
BTTS 58%
O2.5 58%
Odds
Home 1.67
Draw 3.90
Away 4.50
BTTS 1.62
O2.5 1.60
Los Angeles FC
v
New York Red Bulls
USA · Major League Soccer
Thu 10 Sep, 02:30 UTC
Los Angeles FC to win
· 55% model probability
Vancouver Whitecaps
v
Los Angeles Galaxy
USA · Major League Soccer
Thu 10 Sep, 02:30 UTC
Vancouver Whitecaps to win
· 76% model probability
· odds 1.27
Model
BTTS 53%
O2.5 69%
Odds
Home 1.27
Draw 5.75
Away 9.50
BTTS 1.75
O2.5 1.40
San Diego
v
San Jose Earthquakes
USA · Major League Soccer
Thu 10 Sep, 02:30 UTC
San Diego to win
· 56% model probability
· odds 1.67
Model
BTTS 69%
O2.5 72%
Odds
Home 1.67
Draw 4.20
Away 4.20
BTTS 1.36
O2.5 1.33
Portland Timbers
v
St. Louis City
USA · Major League Soccer
Thu 10 Sep, 02:30 UTC
Both teams to score
· 64% model probability
· odds 1.44
Model
BTTS 64%
O2.5 63%
Odds
Home 2.00
Draw 3.75
Away 3.30
BTTS 1.44
O2.5 1.50
Betting MLS in 2026/27
MLS is built differently from every European league we cover, and betting it with European instincts is expensive. The league is engineered for parity — salary caps, allocation money, drafts — so the gap between its best and worst sides is narrower than in any major European division. Dominant seasons happen, but dynasty pricing does not pay here: short favourites in MLS lose at rates that would be shocking in Spain or Germany.
Three structural facts drive the betting profile. First, travel: clubs cross a continent and multiple time zones for away fixtures, and home advantage in MLS is consistently among the strongest in world football — altitude in some venues, summer heat and humidity in others, artificial surfaces in a few. Away form league-wide is poor in a way European bettors underestimate. Second, the calendar: MLS runs spring to autumn, which means it is in mid-season rhythm while European leagues are in pre-season — through the summer months it is the deepest, most data-rich league on our slate. Third, squad rules produce mid-season roster upheaval around the summer transfer and international windows that the market prices slowly.
Scoring runs high — recent seasons have averaged around or above 3 goals per game, helped by attacking roster construction and the travel-weakened away sides — which keeps overs and both teams to score structurally live. The draw rate is unremarkable, but the home/away split is extreme enough that the model's separated home and away ratings matter more here than anywhere else we cover.
How the model handles it
Opposition-adjusted ratings with distinct home and away components are the right tool for a league whose defining feature is venue asymmetry. Expect selections concentrated in home-side match results, overs and BTTS, with particular value in the weeks when European-facing bookmakers are distracted by their own pre-seasons. Cross-conference fixtures, where teams meet rarely, are another spot where the market anchors on reputation and the model on results.
Every MLS selection is archived at kickoff, settled against the odds available at publication, and published in full on the model results page.